JoVE Journal

Cancer Research

This content is Open Access.

A Portal Vein Injection Model to Study Liver Metastasis of Breast Cancer

Transcript

A surgical procedure was developed to deliver mammary tumor cells to the murine liver via portal vein injection. This model permits investigation of late stages of liver metastasis in a fully immune competent host, including tumor cell extravasation, seeding, survival, and metastatic outgrowth in the liver.

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