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Pathological Analysis of Lung Metastasis Following Lateral Tail-Vein Injection of Tumor Cells (Video) | JoVE

DOI :

10.3791/61270-v

May 20th, 2020

May 20th, 2020

7,762 Views

1Department of Radiation Oncology, Arthur G. James Comprehensive Cancer Center and Richard L. Solove Research Institute, The Ohio State University Medical Center, 2Department of Veterinary Biosciences, Comparative Pathology and Digital Imaging Shared Resource, The Ohio State University

Intravenous injection of cancer cells is often used in metastasis research, but the metastatic tumor burden can be difficult to analyze. Herein, we demonstrate a tail-vein injection model of metastasis and include a novel approach to analyze the resulting metastatic lung tumor burden.

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