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Intracarotid Cancer Cell Injection to Produce Mouse Models of Brain Metastasis

DOI :

10.3791/55085-v

February 8th, 2017

February 8th, 2017

24,795 Views

1Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center

Brain metastasis has become an urgent unmet medical need as its incidence has increased while therapeutic options have remained palliative. Creating experimental animal models of brain metastasis via intracarotid arterial injection of cancer cells facilitates mechanistic studies of the disease biology and evaluation of novel intervention regimens.

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Intracarotid Cancer Cell Injection

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