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A Doxorubicin-induced Cardiomyopathy Model in Adult Zebrafish

DOI :

10.3791/57567-v

June 7th, 2018

June 7th, 2018

9,506 Views

1Clinical and Translational Sciences Track, Mayo Clinic Graduate School of Biomedical Sciences, 2Department of Biochemistry and Molecular Biology, Mayo Clinic, 3Division of Cardiovascular Diseases, Mayo Clinic, 4Institute of Life Science, Beijing University of Chinese Medicine

A method to generate a doxorubicin-induced cardiomyopathy model in adult zebrafish (Danio rerio) is described here. Two alternative ways of intraperitoneal injection are presented and conditions to reduce variations among different experimental groups are discussed.

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Doxorubicin induced Cardiomyopathy Model

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