Synthesis and Characterization of Placental Chondroitin Sulfate A (plCSA)-Targeting Lipid-Polymer Nanoparticles

8.6K Views

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05:55 min

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September 18th, 2018

DOI :

10.3791/58209-v

September 18th, 2018

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Baozhen Zhang*¹, Mingbin Zheng*²^,³, Lintao Cai², Xiujun Fan¹

¹Laboratory for Reproductive Health, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences (CAS), ²Guangdong Key Laboratory of Nanomedicine, CAS Key Lab for Health Informatics, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences (CAS), ³Department of Chemistry, Guangdong Medical University

Summary

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Keywords Placental Chondroitin Sulfate A

PlCSA

Lipid polymer Nanoparticles

Targeted Drug Delivery

Chapters in this video

0:04

Title

0:35

Synthesis of DNPs

1:34

Conjugation of Peptides to DNPs

2:54

Fluorescence Microscopy Assessment of pICSA-Targeted Nanoparticle Uptake in Choriocarcinoma (JEG3) Cells

4:18

Results: Characterization and Cellular Uptake of plCSA-DNPs

5:12

Conclusion

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