Workflow and Tools for Crystallographic Fragment Screening at the Helmholtz-Zentrum Berlin
5.5K Views
•
06:29 min
•
March 3rd, 2021
DOI :
March 3rd, 2021
•Jan Wollenhaupt1, Tatjana Barthel1,2, Gustavo M. A. Lima3, Alexander Metz4, Dirk Wallacher5, Elmir Jagudin3, Franziska U. Huschmann1,4, Thomas Hauß1, Christian G. Feiler1, Martin Gerlach1, Michael Hellmig1, Ronald Förster1, Michael Steffien1, Andreas Heine4, Gerhard Klebe4, Uwe Mueller1, Manfred S. Weiss1
1Macromolecular Crystallography, Helmholtz-Zentrum Berlin, 2Structural Biochemistry Group, Institute for Chemistry and Biochemistry, Freie Universität Berlin, 3BioMAX, MAX IV Laboratory, 4Drug Design Group, Institute of Pharmaceutical Chemistry, Philipps-Universität Marburg, 5Department Sample Environment, Helmholtz-Zentrum Berlin
Chapters in this video
0:04
Introduction
1:01
Soaking Crystals
3:14
Harvesting Crystals
4:46
Results: Photographic Snapshots of Some Crystalline Samples and Crystallographic Fragment Screening
5:55
Conclusion
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