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Establishment of an Electrophysiological Platform for Modeling ALS with Regionally-Specific Human Pluripotent Stem Cell-Derived Astrocytes and Neurons

2.2K Views

11:52 min

August 26th, 2021

DOI :

10.3791/62726-v

August 26th, 2021


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Electrophysiological Platform

Chapters in this video

0:04

Introduction

0:48

Maintaining Non-Confluent Human Induced Pluripotent Stem Cells

2:58

Diffrentiation of NPC into Motor Neuron

3:46

Co-Culturing Motor Neurons and Astrocytes in Multi-Electrode Array Plates

7:42

Multi-Electrode Array Recording

8:16

Pharmacological Assays on Multi-Electrode Array

9:01

Results: Human Pluripotent Stem Cell-Derived Motor Neurons and Astrocytes

11:09

Conclusion

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