Purification of Sphingosine 1-Phosphate Receptors (S1PRs)-G Protein Complex
2:16
Electron Microscopy to Resolve the S1PRs Structure
7:56
S1PRs-Gi Mediated cAMP Inhibition Assay
10:33
Results: Purification and Analysis of S1PRs-Gi Complex
11:48
Conclusion
Transcript
We addressed the activation and drug recalculation moods of S1PRS by crew, EM manipulations and GI inhab state A M P A and less significant foundation for developing a drug that solidly targets S1PRS Advancements in make it possible to virulize ma
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S1P exerts its diverse physiological effects through the S1P receptors (S1PRs) subfamily. Here, a pipeline is described to expound on the structures and function of S1PRs.