Rat Burn Model to Study Full-Thickness Cutaneous Thermal Burn and Infection

4.4K Views

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08:40 min

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August 23rd, 2022

DOI :

10.3791/64345-v

August 23rd, 2022

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Rajnikant Sharma¹, Shekhar Yeshwante¹, Quentin Vallé¹, Maytham Hussein², Varsha Thombare², Sean Michael McCann¹, Robert Maile³^,⁴^,⁵, Jian Li⁶, Tony Velkov², Gauri Rao¹

¹UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, ²Department of Biochemistry & Pharmacology, School of Biomedical Sciences, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, ³Department of Microbiology & Immunology, University of North Carolina School of Medicine, ⁴Department of Surgery, University of North Carolina at Chapel Hill, ⁵Curriculum in Toxicology and Environmental Medicine, University of North Carolina at Chapel Hill, ⁶Department of Microbiology, Monash Biomedicine Discovery Institute, Monash University

Summary

Explore More Videos

Rat Burn Model

Full thickness Cutaneous Burn

Burn Induction Method

Animal Models

Intraperitoneal Injection

Morphine Pain Management

Copper Rod Burn Technique

Pseudomonas Aeruginosa

Staphylococcus Aureus Culture

Chapters in this video

0:05

Introduction

0:57

Preparing Rats for the Burn Injury

1:54

Inducing the Burn Injury in Rats

3:20

Preparation of Bacterial Inoculum and Infection

4:26

Evaluation of the Burn Injury and Postprocessing of Rat Samples and Bacterial Enumeration

5:37

Results: A Simple and Reproducible Rat Burn Infection Model

7:59

Conclusion

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