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Somatic Genome-Engineered Mouse Models Using In Vivo Microinjection and Electroporation

DOI :

10.3791/65131-v

8:06 min

May 5th, 2023

May 5th, 2023

716 Views

1Rosalind and Morris Goodman Cancer Research Institute, McGill University, 2Department of Human Genetics, McGill University, 3McGill Integrated Core for Animal Modeling (MICAM), McGill University

This protocol describes microinjection and in vivo electroporation for regionally restricted CRISPR-mediated genome editing in the mouse oviduct.

Tags

Somatic Genome Engineering

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