Results: Understanding Microtubule Dynamics of Glioblastoma Cells via Live Imaging of Zebrafish Larval Xenografts
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This method is dedicated to the investigation of the role of microtubules during brain cancer invasion by coupling the atopic injection of brain cancer cell in zebrafish to the subcellular intravital imaging. The main advantage of the technique li
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We report a technique permitting live imaging of microtubule dynamics in glioblastoma (GBM) cells invading a vertebrate brain tissue. Coupling the orthotopic injection of fluorescently tagged GBM cells into a transparent zebrafish brain with high-resolution intravital imaging allows the measurement of cytoskeleton dynamics during in situ cancer invasion.