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Use of a Wireless Video-EEG System to Monitor Epileptiform Discharges Following Lateral Fluid-Percussion Induced Traumatic Brain Injury

DOI :

10.3791/59637-v

9:16 min

June 21st, 2019

24,619 Views

1Department of Neurosurgery, Jacobs School of Medicine and Biomedical Science, 2Comparative Medicine Laboratory Animal Facilities, University at Buffalo, 3emka Technologies

Here we present a protocol to induce severe TBI with the lateral fluid percussion injury (FPI) model in adult, male Wistar rats. We also demonstrate the use of a wireless telemetry system to collect continuous video-EEG recordings and monitor for epileptiform discharges consistent with post-traumatic epileptogenesis. 

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