LNP Hydrodynamic Size and Polydispersity Measurement
7:02
LNP Zeta Potential Measurement
7:40
Results: Representative LNP Formulation and Characterization
9:08
Conclusion
필기록
This protocol can be used to produce nucleic acid encapsulated lipid nanoparticles with high reproducibility and speed and low volumes. The formulation parameters can be tuned to achieve a desired bio distribution based on the clinical application
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Lipid nanoparticles are developed using a microfluidic mixing platform approach for mRNA and DNA encapsulation.