Spontaneous Murine Model of Anaplastic Thyroid Cancer

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1.5K Views

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05:39 min

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February 3rd, 2023

DOI :

10.3791/64607-v

February 3rd, 2023

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Huayun Yan¹, Yingfang Ma¹, Xinyue Zhou², Yushuang He³, Yang Liu², Carlos Caulin⁴, Leiming Wang⁵, Heng Xu¹^,⁶, Han Luo²^,⁶

¹State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center, ²Division of Thyroid Surgery, Laboratory of Thyroid and Parathyroid Disease, Frontiers Science Center for Disease-Related Molecular Network, Department of General Surgery, West China Hospital, Sichuan University, ³Department of Ultrasound, West China Hospital of Sichuan University, Sichuan University, ⁴Department of Otolaryngology-Head & Neck Surgery and University of Arizona Cancer Center, University of Arizona, ⁵Center for Translational Medicine, Shenzhen Bay Laboratory, ⁶Division of Laboratory Medicine/Research Centre of Clinical Laboratory Medicine, West China Hospital, Sichuan University

Podsumowanie

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MATC Tumors

Anaplastic Thyroid Cancer

Oncogenesis

Drug Discovery

Immune Microenvironment

Gene Functions

Thyroid Tumor Progression

Prognosis Improvement

Tamoxifen Administration

Tissue Extraction

Dissection Techniques

Pathological Information

Sterile PBS

Thyroid Gland Dissection

Vernier Calipers

Paraformaldehyde Solution

Preservation Techniques

Rozdziały w tym wideo

0:04

Introduction

1:00

Tamoxifen‐Induced TBP Mice

1:31

Dissection and Imaging of Mouse Thyroid and Metastatic Tumors

3:35

Results: Tumor Growth Assessment in Tamocifen‐Induced TBP Mice

5:10

Conclusion

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