October 2nd, 2014
•Established cancer cell lines and xenografts have been the mainstay of cancer research for the past several decades. However, recent evidence suggests that therapeutic response is greatly influenced by the tumor cell microenvironment. Therefore, we have developed an ex vivo analysis of primary tumor specimens for drug development purposes.
Tags
Vídeos Relacionados
Thermal Ablation for the Treatment of Abdominal Tumors
Monitoring Tumor Metastases and Osteolytic Lesions with Bioluminescence and Micro CT Imaging
A High-throughput Automated Platform for the Development of Manufacturing Cell Lines for Protein Therapeutics
A Novel High-resolution In vivo Imaging Technique to Study the Dynamic Response of Intracranial Structures to Tumor Growth and Therapeutics
Pre-clinical Evaluation of Tyrosine Kinase Inhibitors for Treatment of Acute Leukemia
Adaptation of Semiautomated Circulating Tumor Cell (CTC) Assays for Clinical and Preclinical Research Applications
A Preclinical Murine Model of Hepatic Metastases
Isolated Hepatic Perfusion as a Treatment for Liver Metastases of Uveal Melanoma
Using Micro-computed Tomography for the Assessment of Tumor Development and Follow-up of Response to Treatment in a Mouse Model of Lung Cancer
Generation of Microtumors Using 3D Human Biogel Culture System and Patient-derived Glioblastoma Cells for Kinomic Profiling and Drug Response Testing
SOBRE A JoVE
Copyright © 2024 MyJoVE Corporation. Todos os direitos reservados