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Chapter 5

Protein Structure

Что такое белки?
Что такое белки?
Proteins are polymers of amino acids linked together by peptide bonds. Proteins and polypeptides are interchangeably used to refer to long chains of amino ...
Организация белка
Организация белка
Proteins are polymers of amino acid residues. They are versatile and responsible for different cellular functions, including DNA replication, molecular ...
Сворачивание белка
Сворачивание белка
Proteins are chains of amino acids linked together by peptide bonds. Upon synthesis, a protein folds into a three-dimensional conformation, critical to ...
Семейства белков
Семейства белков
Protein families are groups of homologous proteins; that is, they have similarities in amino acid sequences and three-dimensional structures. Protein ...
Сохранение белковых доменов
Сохранение белковых доменов
Protein domains are small structurally independent units that are part of a single amino acid chain.  Although these domains are often structurally ...
Глобулярные и волокнистые белки
Глобулярные и волокнистые белки
Many proteins can be classified into two distinct subtypes - globular or fibrous. These two types differ in their shapes and solubilities. Globular ...
Внутренне неупорядоченные белки
Внутренне неупорядоченные белки
Intrinsically disordered proteins are a group of proteins that do not fold into specific three-dimensional structures. Their structural flexibility allows ...
Сборка белкового комплекса
Сборка белкового комплекса
Proteins can form homomeric complexes with another unit of the same protein or heteromeric complexes with different types.  Most protein complexes ...
Конъюгированные белки
Конъюгированные белки
Simple proteins and protein complexes contain only amino acids. In contrast, many other proteins, called conjugated proteins, covalently bond with ...
Амилоидные фибриллы
Амилоидные фибриллы
Amyloid fibrils are aggregates of misfolded proteins.  Under most circumstances, misfolded proteins are either refolded by chaperone proteins or ...
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