The overall goal of this procedure is to consistently produce abdominal adhesions in the mouse while minimizing mortality. This method can help answer key questions in the field of abdominal adhesions, such as what cells, macromolecules, signaling
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Abdominal adhesions that form after surgery are a major cause of pain, infertility, and hospitalization and reoperation for small bowel obstruction. Our surgical procedure for creating abdominal adhesions in mice is a reliable tool to study the mechanisms underlying the formation of adhesions.