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Mouse Models for Graft Arteriosclerosis

DOI :

10.3791/50290-v

May 14th, 2013

May 14th, 2013

13,401 Views

1Department of Surgery, Yale University School of Medicine , 2Department of Pathology, Yale University School of Medicine

We describe protocols for our mouse graft arteriosclerois (GA) models which involve interposition of a mouse vessel segment into a recipient of the same inbred strain. By backcrossing additional genetic changes into the vessel donor, the model can assess the effect of specific genes on GA.

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