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Intralymphatic Immunotherapy and Vaccination in Mice

DOI :

10.3791/51031-v

February 2nd, 2014

February 2nd, 2014

22,203 Views

1Department of Dermatology, University Hospital Zurich

Prophylactic and therapeutic vaccination often fails to stimulate strong immune responses due to week drainage of the vaccine to lymph nodes and consequently poor involvement of immune cells. By direct injection of vaccine to lymph nodes, so-called intralymphatic injection, vaccine efficacy can be strongly improved and vaccine doses can be reduced.

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