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Renal Ischaemia Reperfusion Injury: A Mouse Model of Injury and Regeneration

DOI :

10.3791/51816-v

June 7th, 2014

June 7th, 2014

48,272 Views

1MRC Centre for Inflammation Research, University of Edinburgh

The mouse model of renal ischaemia reperfusion injury described here comprises of a right nephrectomy that provides control tissue and clamping of the left renal pedicle to induce ischaemia that results in acute kidney injury. This model uses a midline laparotomy approach with all steps performed via one incision.

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Renal Ischaemia Reperfusion Injury

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