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Identification of Functional Protein Regions Through Chimeric Protein Construction

DOI :

10.3791/58786-v

January 8th, 2019

January 8th, 2019

10,114 Views

1Department of Cardiac Development and Remodelling, Max Planck Institute for Heart and Lung Research, 2Partner site Rhein-Main, German Centre for Cardiovascular Research (DZHK)

Structurally related proteins frequently exert distinct biological functions. The exchange of equivalent regions of these proteins in order to create chimeric proteins constitutes an innovative approach to identify critical protein regions that are responsible for their functional divergence.

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Functional Protein Regions

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