August 15th, 2019
•Here, we present a protocol using a mouse positioning device that enables the appropriate placement of mice for the intranasal administration of a brain-targeting peptide-siRNA formulation enabling effective gene silencing in the central nervous system.
Related Videos
Induction of Experimental Autoimmune Hypophysitis in SJL Mice
Using Bioluminescent Imaging to Investigate Synergism Between Streptococcus pneumoniae and Influenza A Virus in Infant Mice
Development of Cell-type specific anti-HIV gp120 aptamers for siRNA delivery
Characterization of Inflammatory Responses During Intranasal Colonization with Streptococcus pneumoniae
Culturing Microglia from the Neonatal and Adult Central Nervous System
The Mesenteric Lymph Duct Cannulated Rat Model: Application to the Assessment of Intestinal Lymphatic Drug Transport
Applying Fluorescence Resonance Energy Transfer (FRET) to Examine Effector Translocation Efficiency by Coxiella burnetii during siRNA Silencing
Development of a Hepatitis B Virus Reporter System to Monitor the Early Stages of the Replication Cycle
Analysis of Microglia and Monocyte-derived Macrophages from the Central Nervous System by Flow Cytometry
A Novel Feeder-free System for Mass Production of Murine Natural Killer Cells In Vitro
ABOUT JoVE
Copyright © 2024 MyJoVE Corporation. All rights reserved