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Delivery of Antibodies into the Murine Brain via Convection-enhanced Delivery

DOI :

10.3791/59675-v

July 18th, 2019

July 18th, 2019

7,912 Views

1Institute of Laboratory Animal Science, University of Zurich

Convection-enhanced delivery (CED) is a method enabling effective delivery of therapeutics into the brain by direct perfusion of large tissue volumes. The procedure requires the use of catheters and an optimized injection procedure. This protocol describes a methodology for CED of an antibody into a mouse brain.

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Keywords Convection enhanced Delivery

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