Results: Behavioral Apparatus, Spatial Memory, and Neuronal Death
12:32
Conclusion
Transcript
Cognitive impairment is one of the most common co-morbidities in temporal lobe epilepsy. We will present a protocol describing how to assess memory impairment using a mouse model of chronic epilepsy. Novel object location, novel object recognition
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This article presents experimental procedures for assessing memory impairments in pilocarpine-induced epileptic mice. This protocol can be used to study the pathophysiologic mechanisms of epilepsy-associated cognitive decline, which is one of the most common comorbidities in epilepsy.