A Syngeneic Orthotopic Osteosarcoma Sprague Dawley Rat Model with Amputation to Control Metastasis Rate
3.5K Views
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07:31 min
•
May 3rd, 2021
DOI :
May 3rd, 2021
•Shun Ishiyama1,2,3,4, Casey Kissel5, Xin Guo1, Alexis Howard6, Harumi Saeki7, Tomoaki Ito8, Polina Sysa-Shah9, Hajime Orita10, Kazuhiro Sakamoto4, Kathleen Gabrielson1,2
1Department of Molecular and Comparative Pathobiology, The Johns Hopkins University School of Medicine, 2Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, 3Department of Surgery, Johns Hopkins University School of Medicine, 4Department of Coloproctological Surgery, Juntendo University Faculty of Medicine, 5Program for Comparative Medicine, Gene Therapy Program, Perelman School of Medicine, University of Pennsylvania, 6Tuskegee College of Veterinary Medicine, 7Department of Human Pathology, Juntendo University Faculty of Medicine, 8Department of Surgery, Juntendo University Shizuoka Hospital, Juntendo University School of Medicine, 9Department of Urology, The Johns Hopkins School of Medicine, 10Department of Gastroenterology and Minimally Invasive Surgery, Juntendo University Faculty of Medicine
Chapters in this video
0:04
Introduction
1:19
Intratibial Osteosarcoma (OS) Cell Injection
2:41
Doxorubicin Intravenous Administration
3:36
Hind Limb Amputation
5:08
Results: Representative Rat OS Imaging and Analysis
6:43
Conclusion
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