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Production of Membrane-Filtered Phase-Shift Decafluorobutane Nanodroplets from Preformed Microbubbles

DOI :

10.3791/62203-v

March 23rd, 2021

March 23rd, 2021

2,414 Views

1Department of Bioengineering, The University of Texas at Dallas, 2Department of Radiology, The University of Texas Southwestern

This protocol describes a method of generating large volumes of lipid encapsulated decafluorobutane microbubbles using probe-tip sonication and subsequently condensing them into phase-shift nanodroplets using high-pressure extrusion and mechanical filtration.

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