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Deciphering High-Resolution 3D Chromatin Organization via Capture Hi-C

DOI :

10.3791/64166-v

9:32 min

October 14th, 2022

October 14th, 2022

1,736 Views

1EMBL: European Molecular Biology Laboratory, 2Institut Curie, 3Agilent Technologies, 4Genmab BV, 5Collège de France

This protocol describes the Capture Hi-C method used to characterize the 3D organization of megabased-sized targeted genomic regions at high-resolution, including boundaries of topologically associating domains (TADs) and long-range chromatin interactions between regulatory and other DNA sequence elements.

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Capture Hi C

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