Preparation of Unmodified and Fluorescein Isothiocyanate (FITC)-Modified Lysine-Tyrosine-Phenylalanine (KYF) Tripeptide
5:59
Synthesis of FITC-KYF-Stabilized or KYF-Stabilized Nanoemulsion with Oleic Acid-Pt(II) Cores (FITC-KYF-Pt-NE or KYF-Pt-NE)
8:03
Results: KYF-Pt-NE and FITC-KYF-Pt-NE Characterization
9:43
Conclusion
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Given the wide range of short peptide sequences, this method can be extended to many other nanoparticle designs. Peptide modification can make the system suitable for diagnostic purposes. Encapsulating anti-cancer platinum to drugs with biodegrada
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This protocol describes an efficient method to synthesize a nanoemulsion of an oleic acids-platinum(II) conjugate stabilized with a lysine-tyrosine-phenylalanine (KYF) tripeptide. The nanoemulsion forms under mild synthetic conditions via self-assembly of the KYF and the conjugate.