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In This Article

  • Summary
  • Abstract
  • Introduction
  • Protocol
  • Representative Results
  • Discussion
  • Acknowledgements
  • Materials
  • References
  • Reprints and Permissions

Summary

The present protocol describes the specific process and efficacy of the acupoint application combined with ear plaster therapy for sleep disorders in a patient with acute exacerbation of chronic obstructive pulmonary disease, including medical devices, selection of acupoints, operating methods, and posttreatment care.

Abstract

Chronic Obstructive Pulmonary Disease (COPD) is a lung disease characterized by persistent airflow limitation, which is not fully reversible and progressive. Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) refers to acute changes in respiratory distress, cough, and sputum in COPD patients at baseline levels. Sleep disorders are a very common complication in patients with AECOPD. At present, long-term use of sedative-hypnotics alone has many side effects, such as mental and physical dependence and cognitive impairment. While the efficacy of other special intervention methods is not clear, and the cost is high, there is an urgent need for effective and safe treatment in clinics. Acupoint application and ear plaster therapy are considered the characteristic therapies of traditional Chinese medicine. They have the advantages of small side effects, high safety, and simple procedure. This study will elucidate in detail the specific process and efficacy of the two treatment methods for AECOPD complicated with sleep disorders, including medical devices used, selection of acupoints, procedure, and posttreatment care. This study is intended to provide a new reference for the clinical treatment modality of this type of disease.

Introduction

Chronic obstructive pulmonary disease (COPD) is a disease characterized by incomplete reversibility of airflow limitation, with gradual progression, primarily involving the lungs, but also causing damage to various other organs outside the lungs. Its pathogenesis is mainly related to the regulation of apoptosis and promotion of inflammatory response by radical oxygen species (ROS) during oxidative stress (OS)1, affecting gene transcription and exacerbating protease-antiprotease imbalance finally2. It often causes chronic coughing, coughing up sputum, shortness of breath or difficulty breathing, wheezing, and chest tightn....

Protocol

This is a before and after self-controlled trial of seven patients diagnosed with AECOPD complicated with sleep disorders from the Hospital of Chengdu University of Traditional Chinese Medicine between December 2023 and January 2024. The clinical study protocol was reviewed and approved by the Clinical Research Approval Committee of the Department of Respiratory Medicine, Hospital of Chengdu University of Traditional Chinese Medicine (KY2022031).

1. Patient selection

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Representative Results

Based on the changes before and after treatment, it was found that the total PSQI scores and five components score results of PSQI, including time to fall asleep, sleep quality, sleep time, sleep disorders, and daytime function, were all lower than before, and the differences were statistically significant (P < 0.05). However, there were not many changes before and after treatment regarding sleep efficiency (P = 0.056) and application of medications for sleeping (P = 0.103) (See Tab.......

Discussion

This study combined AA with EPT to explore the procedure and efficacy of the treatment of sleep disorders in patients with AECOPD. AA refers to the external treatment method of grinding specific drugs into powder and then mixing them into a paste with water, white wine or rice wine, vinegar, ginger juice, etc., and finally making the paste, pill, powder, paste, mud, cake and other dosage forms, which are applied to specific acupoints. Reviewing the literature on AA in the treatment of sleep disorder in the past ten years.......

Acknowledgements

This research was supported by the National Natural Science Foundation of China (82374291), 2022 "Tianfu Qingcheng Plan" Tianfu Science and Technology Leading Talents Project (Chuan Qingcheng No. 1090), the National TCM Clinical Excellent Talents Training Program (National TCM Renjiao Letter [2022] No. 1), "100 Talent Plan" Project of Hospital of Chengdu University of Traditional Chinese Medicine (Hospital office [2021] 42), Special subject of scientific research of Sichuan Administration of Traditional Chinese Medicine (2021MS539, 2023MS608), Sichuan Science Technology Program (2023ZYD0050, 24NSFJQ0077),"Hundred Talents Program" of the Hospita....

Materials

NameCompanyCatalog NumberComments
75% alcohol cotton ballsShanghai Honglong Industrial Co., Ltd20231116
Acupoint patchesJiangsu Guangyi Medical Dressing Co., Ltd20230718
Chinese herbal medicineGuangdong Kanghe Pharmaceutical Co.,Ltd230802
Magnetic treatment plasterSuzhou Medical Supplies Factory Co., Ltd233010
Medical disposable sterilization rubber glovesShandong Yuyuan Latex Gloves Co., Ltd230806R22
Medical hand disinfectantsShanghai Likang Disinfection High tech Co., Ltd20230113J
Medical tapeMinnesota Mining Manufacturing Medical Equipment (Shanghai) Co., Ltd23063GO
Sterile cotton swabsShanghai Honglong Medical Equipment Co., Ltd20231108
TweezersYangzhou Huayue Technology Development Co., Ltd20231106

References

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Acupoint ApplicationEar Plaster TherapySleep DisordersChronic Obstructive Pulmonary DiseaseAcute ExacerbationAECOPDTraditional Chinese MedicineTreatment EfficacyClinical Treatment ModalityMedical DevicesAcupoint SelectionPosttreatment Care

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