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Isolation of Fidelity Variants of RNA Viruses and Characterization of Virus Mutation Frequency

DOI :

10.3791/2953-v

18:10 min

June 16th, 2011

June 16th, 2011

29,100 Views

1Viral Populations and Pathogenesis lab and CNRS 3015, Institut Pasteur

The present article describes the steps required to isolate and characterize RNA polymerase fidelity variants of RNA viruses and how to use mutation frequency data to confirm fidelity changes in tissue culture.

Tags

RNA Viruses

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