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Instillation and Fixation Methods Useful in Mouse Lung Cancer Research

DOI :

10.3791/52964-v

August 31st, 2015

August 31st, 2015

27,526 Views

1Bloomberg School of Public Health, Environmental Health Sciences, Johns Hopkins University, 2Department of Medicine, Pulmonary Diseases and Critical Care Medicine, University of North Carolina School of Medicine

The goal of this paper is to describe simple methods that will greatly aid in the setup and analysis of mouse lungs with lung cancer or other pathologies. We present 3 protocols to simply and reliably carry out lung instillations, fixation, and lung volume measurements.

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Instillation Methods

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