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Establishment and Characterization of Small Bowel Neuroendocrine Tumor Spheroids

DOI :

10.3791/60303-v

October 14th, 2019

October 14th, 2019

6,242 Views

1Department of Surgery, University of Iowa Carver College of Medicine, 2High Throughput Screening Facility, University of Iowa Carver College of Medicine, 3Department of Pathology, University of Iowa Carver College of Medicine

Neuroendocrine tumors (NETs) originate from neuroendocrine cells of the neural crest. They are slow growing and challenging to culture. We present an alternative strategy to grow NETs from the small bowel by culturing them as spheroids. These spheroids have small bowel NET markers and can be used for drug testing.

Tags

Small Bowel Neuroendocrine Tumor

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