Identification and Characterization of Immunogenic RNA Species in HDM Allergens that Modulate Eosinophilic Lung Inflammation

5.9K Views

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08:44 min

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May 30th, 2020

DOI :

10.3791/61183-v

May 30th, 2020

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Hamad H. Alanazi¹^,², Li She¹^,³, Xiao-Dong Li¹

¹Department of Microbiology, Immunology and Molecular Genetics, Long School of Medicine, University of Texas Health San Antonio, ²Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, ³Department of Otolaryngology-Head and Neck Surgery, Xiangya Hospital, Central South University

Summary

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Immunogenic RNA

HDM Allergens

Eosinophilic Lung Inflammation

Allergic Inflammation

Respiratory Viral Infections

Chapters in this video

0:04

Introduction

1:02

Dot Blot to Show the Presence of dsRNA Structures in HDM Total RNA

3:54

FACS Analysis to Determine the Effects of HDM RNA on the Infiltration of Eosinophils in BAL and Lung

6:19

Results: dsRNA Structures in HDM RNAs

7:53

Conclusion

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