High-Throughput Screening to Obtain Crystal Hits for Protein Crystallography

3.9K Views

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06:19 min

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March 10th, 2023

DOI :

10.3791/65211-v

March 10th, 2023

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Gabrielle R. Budziszewski¹, M. Elizabeth Snell¹, Tiffany R. Wright¹, Miranda L. Lynch¹, Sarah E. J. Bowman¹^,²

¹National High-Throughput Crystallization Center, Hauptman-Woodward Medical Research Institute, ²Department of Biochemistry, Jacobs School of Medicine and Biomedical Sciences, The State University of New York

Summary

Explore More Videos

High Throughput Screening

Crystal Hits

Protein Crystallography

X ray Diffraction

Structural Biology

Computational Structure Prediction

Micro ED

Serial Crystallography

Imaging Technologies

Crystallization Conditions

Protein Data Bank

Automated Methods

Crystallization Cocktail Components

Optical Methods

National HTX Center

Chapters in this video

0:00

Introduction

1:37

??Oil and Crystallization Cocktail Well Plate Preparation

2:32

Protein Sample Setup and Crystallization

4:08

Image Analysis to Identify Protein Crystals

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