Results: Experimental Timeline and Post Injection Edema Assay
7:34
Conclusion
Transkript
The overall goal of this protocol is to use zebrafish to observe the effect of nephrotoxins such as gentamicin or cisplatin to model acute kidney injury. The main advantage of this technique is that the zebrafish model enables real time imaging of
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Renal injuries incurred from nephrotoxins, which include drugs ranging from antibiotics to chemotherapeutics, can result in complex disorders whose pathogenesis remains incompletely understood. This protocol demonstrates how zebrafish can be used for disease modeling of these conditions, which can be applied to the identification of renoprotective measures.