Results: The Analysis of BLI Correlation with CFU at the Time of Instillation and Longitudinal Follow-up During Treatment
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Conclusion
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The enumeration of colony forming units was limiting the reproducibility of research in the UTI field. Bioluminescence imaging will advance in vivo UTI research on bladder physiology, UTI pathogenesis and susceptibility. Bioluminescence imaging en
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This manuscript describes the intravesical administration of uropathogenic bacteria with a lux operon to induce a urinary tract infection in mice and subsequent longitudinal in vivo analysis of the bacterial load using bioluminescence imaging.