Results: Real-Time Investigation of the Unfolding of an Ensemble Set of Biomolecular Structures by Shear Force
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Conclusion
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This protocol provides a high throughput technique to study the intermolecular binding between DNA and ligands. This technique has demonstrated high throughput in the investigation of massive set of biomolecular structures. It does so by convertin
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Ensemble force spectroscopy (EFS) is a robust technique for mechanical unfolding and real-time sensing of an ensemble set of biomolecular structures in biophysical and biosensing fields.