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Autoradiography as a Simple and Powerful Method for Visualization and Characterization of Pharmacological Targets

42.0K Views

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10:16 min

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March 12th, 2019

DOI :

10.3791/58879-v

March 12th, 2019

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42,020 Views

Nane Griem-Krey¹, Anders Bue Klein¹, Matthias Herth^1,2,3, Petrine Wellendorph¹

¹Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, ²Neurobiology Research Unit and CIMBI, Copenhagen University Hospital, ³Department of Clinical Physiology, Nuclear Medicine & PET, Copenhagen University Hospital

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Keywords Autoradiography

Protein Binding

Pharmacological Targets

Tissue Visualization

Cryostat Sectioning

Radioligand Labeling

Non specific Binding

Spatial Resolution

Digital Imaging

Tissue Preparation

Pharmacological Analysis

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