Microfluidic Device for Recreating a Tumor Microenvironment in Vitro

0:50

Introduction

2:52

Microfluidic Device Fabrication

5:45

Formation of Uniform Tumor Spheroids using the Hanging Drop Method

7:04

Introduction of Spheroids into the Microfluidic Device

9:18

Introduction of Apoptosis-detecting Agent into the Microfluidic Device

10:50

Introduction of Therapeutic Agents into the Microfluidic Device

11:59

Time Lapse Microscopy and Estimation of Drug Diffusivity Coefficients

14:25

Representative Results

15:30

Concluding Remarks