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On-Chip Endothelial Inflammatory Phenotyping

DOI :

10.3791/4169-v

July 21st, 2012

July 21st, 2012

10,699 Views

1Department of Biomedical Engineering, University of California, Davis

Microfluidic flow chambers etched by photolithography and fabricated from PDMS are applied to probe functional outcomes associated with EC dysfunction and inflammation. In a representative experiment, the ability of differential shear stress to modulate monocytic cell adhesion to cytokine activated EC monolayers is demonstrated.

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On Chip Endothelial Inflammatory Phenotyping

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