JoVE Logo
Faculty Resource Center

Sign In

Use of the Invertebrate Galleria mellonella as an Infection Model to Study the Mycobacterium tuberculosis Complex

DOI :

10.3791/59703-v

June 30th, 2019

June 30th, 2019

11,359 Views

1Section of Pediatric Infectious Diseases and Allergy, Department of Medicine, Imperial College London, 2Department of Pharmacy, National University of Singapore, 3MRC Centre for Molecular Bacteriology and Infection, Department of Medicine, Imperial College London

Galleria mellonella was recently established as a reproducible, cheap, and ethically acceptable infection model for the Mycobacterium tuberculosis complex. Here we describe and demonstrate the steps taken to establish successful infection of G. mellonella with bioluminescent Mycobacterium bovis BCG lux.

Tags

Galleria Mellonella

-- Views

Related Videos

article

Introducing Shear Stress in the Study of Bacterial Adhesion

article

Growth of Mycobacterium tuberculosis Biofilms

article

The Insect Galleria mellonella as a Powerful Infection Model to Investigate Bacterial Pathogenesis

article

An Experimental Model to Study Tuberculosis-Malaria Coinfection upon Natural Transmission of Mycobacterium tuberculosis and Plasmodium berghei

article

Use of Galleria mellonella as a Model Organism to Study Legionella pneumophila Infection

article

Establishment and Optimization of a High Throughput Setup to Study Staphylococcus epidermidis and Mycobacterium marinum Infection as a Model for Drug Discovery

article

A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection

article

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates

article

Imaging Mycobacterium tuberculosis in Mice with Reporter Enzyme Fluorescence

article

Modeling Tuberculosis in Mycobacterium marinum Infected Adult Zebrafish

JoVE Logo

Privacy

Terms of Use

Policies

Research

Education

ABOUT JoVE

Copyright © 2024 MyJoVE Corporation. All rights reserved