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Supervised Machine Learning for Semi-Quantification of Extracellular DNA in Glomerulonephritis

DOI :

10.3791/61180-v

June 18th, 2020

June 18th, 2020

6,544 Views

1Department of Medicine, Monash University, 2Monash Micro Imaging, Monash University, 3Immunology Department, Monash Health

Extracellular DNA (ecDNA) released during cell death is proinflammatory and contributes to inflammation. Measurement of ecDNA at the site of injury can determine the efficacy of therapeutic treatment in the target organ. This protocol describes the use of a machine learning tool to automate measurement of ecDNA in kidney tissue.

Tags

Supervised Machine Learning

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