In Vivo Targeting of Xenografted Human Cancer Cells with Functionalized Fluorescent Silica Nanoparticles in Zebrafish
4.5K Views
•
10:26 min
•
May 8th, 2020
DOI :
May 8th, 2020
•Xiaodan Qin*1, Fabrice F. J. Laroche*1, Saquib Ahmed M. A. Peerzade2, Andrew Lam1, Igor Sokolov2,3,4, Hui Feng1
1Departments of Pharmacology and Medicine, Section of Hematology and Medical Oncology, The Cancer Research Center, Boston University School of Medicine, 2Department of Biomedical Engineering, Tufts University, 3Department of Mechanical Engineering, Tufts University, 4Department of Physics, Tufts University
Explore More Videos
Chapters in this video
0:04
Introduction
0:54
Generation of Casper Zebrafish Embryos
2:33
Preparing Materials for Cancer Cell Transplantation
3:34
Preparing Cancer Cells for Transplantation
5:20
Transplantation of Cancer Cells
6:54
Injection of Nanoparticles or Vehicle
7:40
Imaging and Tracking of Nanoparticles and Cancer Cells
8:45
Results: Colocalization of Cancer Cells and Nanoparticles
9:47
Conclusion
Related Videos
08:03
Anticancer Efficacy of Photodynamic Therapy with Lung Cancer-Targeted Nanoparticles
8.9K Views
09:22
Invasive Behavior of Human Breast Cancer Cells in Embryonic Zebrafish
16.5K Views
10:46
In Vivo EPR Assessment of pH, pO2, Redox Status, and Concentrations of Phosphate and Glutathione in the Tumor Microenvironment
8.2K Views
05:55
Synthesis and Characterization of Placental Chondroitin Sulfate A (plCSA)-Targeting Lipid-Polymer Nanoparticles
8.6K Views
11:07
In Vivo Imaging and Quantitation of the Host Angiogenic Response in Zebrafish Tumor Xenografts
6.8K Views
10:29
Semi-automatic PD-L1 Characterization and Enumeration of Circulating Tumor Cells from Non-small Cell Lung Cancer Patients by Immunofluorescence
10.5K Views
09:44
In Vitro Evaluation of Oncogenic Transformation in Human Mammary Epithelial Cells
4.4K Views
10:35
Chemical Conjugation of a Purified DEC-205-Directed Antibody with Full-Length Protein for Targeting Mouse Dendritic Cells In Vitro and In Vivo
3.3K Views
09:57
Evaluation of the In vivo Antitumor Activity of Polyanhydride IL-1α Nanoparticles
2.0K Views
08:31
Fluorescence Microscopy for ATP Internalization Mediated by Macropinocytosis in Human Tumor Cells and Tumor-xenografted Mice
2.7K Views
Copyright © 2025 MyJoVE Corporation. All rights reserved