Toxicity Screens in Human Retinal Organoids for Pharmaceutical Discovery

3.4K Views

07:45 min

March 4th, 2021

DOI :10.3791/62269-v

March 4th, 2021

Transcript

Explore More Videos

Toxic Screens

Chapters in this video

0:04

Introduction

0:47

Deoxysphinganine (deoxySA) Treatment

2:23

Organoid Slice Imaging

3:35

Cell Death Quantification

5:07

Drug Treatment

6:06

Results: Representative Effects of DeoxySA on Retinal Organoid Cell Death

7:03

Conclusion

Related Videos

Medium-Throughput Drug- and Radiotherapy Screening Assay using Patient-Derived Organoids

3.8K Views

An Intestine/Liver Microphysiological System for Drug Pharmacokinetic and Toxicological Assessment

8.0K Views

Multiparametric Tumor Organoid Drug Screening Using Widefield Live-Cell Imaging for Bulk and Single-Organoid Analysis

4.9K Views

Generation of Human Patient iPSC-derived Retinal Organoids to Model Retinitis Pigmentosa

2.7K Views

Generation of Retinal Organoids from Healthy and Retinal Disease-Specific Human-Induced Pluripotent Stem Cells

3.5K Views

Generating Neural Retina from Human Pluripotent Stem Cells

1.3K Views

Long-Term, Serum-Free Cultivation of Organotypic Mouse Retina Explants with Intact Retinal Pigment Epithelium

8.7K Views

Directed Induction of Retinal Organoids from Human Pluripotent Stem Cells

2.9K Views

Retinal Explant of the Adult Mouse Retina as an Ex Vivo Model for Studying Retinal Neurovascular Diseases

4.2K Views

High Throughput SiRNA Screening for Chloropicrin and Hydrogen Fluoride-Induced Cornea Epithelial Cell Injury

5.9K Views