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Toxicity Screens in Human Retinal Organoids for Pharmaceutical Discovery (Video) | JoVE

DOI :

10.3791/62269-v

March 4th, 2021

March 4th, 2021

2,706 Views

1Lowy Medical Research Institute, 2The Scripps Research Institute

Here we present a step-by-step protocol to generate mature human retinal organoids and utilize them in a photoreceptor toxicity assay to identify pharmaceutical candidates for the age-related retinal degenerative disease macular telangiectasia type 2 (MacTel).

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