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Probing Structural and Dynamic Properties of Trafficking Subcellular Nanostructures by Spatiotemporal Fluctuation Spectroscopy

DOI :

10.3791/62790-v

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8:17 min

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August 16th, 2021

August 16th, 2021

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1,503 Views

1NEST Laboratory, Scuola Normale Superiore, 2Center for Nanotechnology Innovation@NEST CNI@NEST

Imaging-derived mean square displacement (iMSD) analysis is applied to macropinosomes to highlight their intrinsic time-evolving nature in terms of structural and dynamic properties. Macropinosomes are then compared to insulin secretory granules (ISGs) as a reference for subcellular structures with time-invariant average structural/dynamic properties.

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Structural Properties

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