A Porcine Heterotopic Heart Transplantation Protocol for Delivery of Therapeutics to a Cardiac Allograft
2.5K Views
•
08:30 min
•
February 14th, 2022
DOI :
February 14th, 2022
•Michelle Mendiola Pla1, Amy Evans2, Franklin H. Lee3, Yuting Chiang1, Muath Bishawi1, Andrew Vekstein1, Lillian Kang1, Diego Zapata4, Ryan Gross3, Alexis Carnes2, Lynden E. Gault5, Julie A. Balko6, Desiree Bonadonna2, Sam Ho5, Paul Lezberg7, Benjamin S. Bryner1, Jacob N. Schroder1, Carmelo A. Milano1, Dawn E. Bowles3
1Division of Cardiothoracic Surgery, Department of Surgery, Duke University, 2Perfusion Services, Duke University, 3Division of Surgical Sciences, Department of Surgery, Duke University, 4Division of Laboratory Animal Resources, Duke University, 5Gift of Hope Organ and Tissue Donor Network, 6College of Veterinary Medicine, North Carolina State University, 7TransMedics, Inc
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Chapters in this video
0:04
Introduction
1:00
Median Sternotomy of the Donor Pig
1:56
Cardiac Arrest and Cardiectomy of the Donor Pig
3:39
Back-Table Preparation of the Donor Heart and Reanimating the Heart
4:47
Preparation of the Recipient and Laparotomy with Vascular Exposure
5:45
Heterotopic Implantation of the Cardiac Graft and Closure of the Laparotomy
6:49
Results: Analysis of Perfusion Parameters and Transplanted Heart
7:36
Conclusion
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