JoVE Logo
Faculty Resource Center

Sign In

CAM-Delam Assay to Score Metastatic Properties by Quantifying Delamination and Invasion Capacity of Cancer Cells

DOI :

10.3791/64025-v

12:14 min

June 2nd, 2022

June 2nd, 2022

2,121 Views

1Umeå Centre for Molecular Medicine, Umeå University, 2Department of Histology and Embryology, Medical Academy, Lithuanian University of Health Sciences

The CAM-Delam assay to evaluate the metastatic capacity of cancer cells is relatively fast, easy, and cheap. The method can be used for unraveling the molecular mechanisms regulating metastasis formation and for drug screening. An optimized assay for analyzing human tumor samples could be a clinical method for personalized cancer treatment.

Tags

CAM Delam Assay

-- Views

Related Videos

article

Coculture Assays to Study Macrophage and Microglia Stimulation of Glioblastoma Invasion

article

Advanced Animal Model of Colorectal Metastasis in Liver: Imaging Techniques and Properties of Metastatic Clones

article

Practical Considerations in Studying Metastatic Lung Colonization in Osteosarcoma Using the Pulmonary Metastasis Assay

article

Moving Upwards: A Simple and Flexible In Vitro Three-dimensional Invasion Assay Protocol

article

Analysis of Cancer Cell Invasion and Anti-metastatic Drug Screening Using Hydrogel Micro-chamber Array (HMCA)-based Plates

article

A Spheroid Killing Assay by CAR T Cells

article

Real Time Detection of In Vitro Tumor Cell Apoptosis Induced by CD8+ T Cells to Study Immune Suppressive Functions of Tumor-infiltrating Myeloid Cells

article

Fully Human Tumor-based Matrix in Three-dimensional Spheroid Invasion Assay

article

Micromanipulation of Circulating Tumor Cells for Downstream Molecular Analysis and Metastatic Potential Assessment

article

Evaluating the Differentiation Capacity of Mouse Prostate Epithelial Cells Using Organoid Culture

JoVE Logo

Privacy

Terms of Use

Policies

Research

Education

ABOUT JoVE

Copyright © 2024 MyJoVE Corporation. All rights reserved