Post Procedure Follow-Up and Experiment Termination
4:18
Micro-Computed Tomography (Micro-CT)
5:42
Contouring
6:54
Histology
8:27
Results: Representative Micro-CT and Histological Analyses
9:41
Conclusion
副本
Our protocol enables the study of periapical periodontitis in an accessible and controlled mouse model. Therefore, this protocol has advantages over patient samples or in-vitro models. The main advantages of this technique are that the mouse has b
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Here, we present a protocol to locally induce apical periodontitis in mice. We show how to drill a hole in the mouse's tooth and expose its pulp, in order to cause local inflammation. Analysis methods to investigate the nature of this inflammation, such as micro-CT and histology, are also demonstrated.
