The authors have no acknowledgements.

The protocol illustrated here follows the guidelines of the human research ethics committee at Brigham and Women&#39;s Hospital.
1. Preoperative Protocol
<ol>
	<li>Assess patients with spinal pathology in clinic and determine eligibility for spinal surgery. Perform neurological assessment and obtain CT or MRI scan to identify spinal lesion.</li>
	<li>Include patients who have an intradural pathology such as schwannoma, ependymoma, meningioma, astrocytoma, etc.; or patients who have ...

<ol>
	<li>Reid, M. H. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Ultrasonic+visualization+of+a+cervical+cord+cystic+astrocytoma.">Ultrasonic visualization of a cervical cord cystic astrocytoma.</a> AJR. American Journal of Roentgenology. 131 (5), 907-908 (1978).</li><li>Dohrmann, G. J., Rubin, J. M. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Intraoperative+ultrasound+imaging+of+the+spinal+cord:+syringomyelia,+cysts,+and+tumors--a+preliminary+report.">Intraoperative ultrasound imaging of the spinal cord: syringomyelia, cysts, and tumors--a preliminary report.</a> Surgical Neurology. 18 (6), 395-399 (1982).</li><li>Rubin, J. M., Dohrmann, G. J. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Use+of+ultrasonically+guided+probes+and+catheters+in+neurosurgery.">Use of ultrasonically guided probes and catheters in neurosurgery.</a> Surgical Neurology. 18 (2), 143-148 (1982).</li><li>Braun, I. F., Raghavendra, B. N., Kricheff, I. I. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Spinal+cord+imaging+using+real-time+high-resolution+ultrasound.">Spinal cord imaging using real-time high-resolution ultrasound.</a> Radiology. 147 (2), 459-465 (1983).</li><li>Hutchins, W. W., Vogelzang, R. L., Neiman, H. L., Fuld, I. L., Kowal, L. E. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Differentiation+of+tumor+from+syringohydromyelia:+intraoperative+neurosonography+of+the+spinal+cord.">Differentiation of tumor from syringohydromyelia: intraoperative neurosonography of the spinal cord.</a> Radiology. 151 (1), 171-174 (1984).</li><li>Juthani, R. G., Bilsky, M. H., Vogelbaum, M. A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Current+Management+and+Treatment+Modalities+for+Intramedullary+Spinal+Cord+Tumors.">Current Management and Treatment Modalities for Intramedullary Spinal Cord Tumors.</a> Current Treatment Options in Oncology. 16 (8), 39 (2015).</li><li>Knake, J. E., Gabrielsen, T. O., Chandler, W. F., Latack, J. T., Gebarski, S. S., Yang, P. J. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Real-time+sonography+during+spinal+surgery.">Real-time sonography during spinal surgery.</a> Radiology. 151 (2), 461-465 (1984).</li><li>Montalvo, B. M., Quencer, R. M., Green, B. A., Eismont, F. J., Brown, M. J., Brost, P. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Intraoperative+sonography+in+spinal+trauma.">Intraoperative sonography in spinal trauma.</a> Radiology. 153 (1), 125-134 (1984).</li><li>Montalvo, B. M., Quencer, R. M. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Intraoperative+sonography+in+spinal+surgery:+current+state+of+the+art.">Intraoperative sonography in spinal surgery: current state of the art.</a> Neuroradiology. 28 (5-6), 551-590 (1986).</li><li>Pasto, M. E., Rifkin, M. D., Rubenstein, J. B., Northrup, B. E., Cotler, J. M., Goldberg, B. B. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Real-time+ultrasonography+of+the+spinal+cord:+intraoperative+and+postoperative+imaging.">Real-time ultrasonography of the spinal cord: intraoperative and postoperative imaging.</a> Neuroradiology. 26 (3), 183-187 (1984).</li><li>Mari, A. R., Shah, I., Imran, M., Ashraf, J. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Role+of+intraoperative+ultrasound+in+achieving+complete+resection+of+intra-axial+solid+brain+tumours.">Role of intraoperative ultrasound in achieving complete resection of intra-axial solid brain tumours.</a> JPMA. The Journal of the Pakistan Medical Association. 64 (12), 1343-1347 (2014).</li><li>Ivanov, M., Budu, A., Sims-Williams, H., Poeata, I. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Using+Intraoperative+Ultrasonography+for+Spinal+Cord+Tumor+Surgery.">Using Intraoperative Ultrasonography for Spinal Cord Tumor Surgery.</a> World Neurosurgery. 97, 104-111 (2017).</li><li>Blumenkopf, B., Daniels, T. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Intraoperative+ultrasonography+(IOUS)+in+thoracolumbar+fractures.">Intraoperative ultrasonography (IOUS) in thoracolumbar fractures.</a> Journal of Spinal Disorders. 1 (1), 86-93 (1988).</li><li>McGahan, J. P., Benson, D., Chehrazi, B., Walter, J. P., Wagner, F. C. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Intraoperative+sonographic+monitoring+of+reduction+of+thoracolumbar+burst+fractures.">Intraoperative sonographic monitoring of reduction of thoracolumbar burst fractures.</a> AJR. American Journal of roentgenology. 145 (6), 1229-1232 (1985).</li><li>Quencer, R. M., Montalvo, B. M., Eismont, F. J., Green, B. A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Intraoperative+spinal+sonography+in+thoracic+and+lumbar+fractures:+evaluation+of+Harrington+rod+instrumentation.">Intraoperative spinal sonography in thoracic and lumbar fractures: evaluation of Harrington rod instrumentation.</a> AJR. American Journal of roentgenology. 145 (2), 343-349 (1985).</li><li>Sosna, J., Barth, M. M., Kruskal, J. B., Kane, R. A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Intraoperative+sonography+for+neurosurgery.">Intraoperative sonography for neurosurgery.</a> Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine. 24 (12), 1671-1682 (2005).</li><li>Raymond, C. A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Brain,+spine+surgeons+say+yes+to+ultrasound.">Brain, spine surgeons say yes to ultrasound.</a> JAMA. 255 (17), 2258-2262 (1986).</li><li>Toktas, Z. O., Sahin, S., Koban, O., Sorar, M., Konya, D. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Is+intraoperative+ultrasound+required+in+cervical+spinal+tumors?+A+prospective+study.">Is intraoperative ultrasound required in cervical spinal tumors? A prospective study.</a> Turkish Neurosurgery. 23 (5), 600-606 (2013).</li><li>. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=.">.</a> Surgical Approaches to the Spine. , (2015).</li><li>Friedman, J. A., Wetjen, N. M., Atkinson, J. L. D. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Utility+of+intraoperative+ultrasound+for+tumors+of+the+cauda+equina.">Utility of intraoperative ultrasound for tumors of the cauda equina.</a> Spine. 28 (3), 288-290 (2003).</li><li>Zhou, H., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Intraoperative+ultrasound+assistance+in+treatment+of+intradural+spinal+tumours.">Intraoperative ultrasound assistance in treatment of intradural spinal tumours.</a> Clinical Neurology and Neurosurgery. 113 (7), 531-537 (2011).</li><li>Harrop, J. S., Ganju, A., Groff, M., Bilsky, M. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Primary+intramedullary+tumors+of+the+spinal+cord.">Primary intramedullary tumors of the spinal cord.</a> Spine. 34, 69-77 (2009).</li><li>Quencer, R. M., Montalvo, B. M. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Normal+intraoperative+spinal+sonography.">Normal intraoperative spinal sonography.</a> AJR. American journal of roentgenology. 143 (6), 1301-1305 (1984).</li><li>Aoyama, T., Hida, K., Akino, M., Yano, S., Iwasaki, Y. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Detection+of+residual+disc+hernia+material+and+confirmation+of+nerve+root+decompression+at+lumbar+disc+herniation+surgery+by+intraoperative+ultrasound.">Detection of residual disc hernia material and confirmation of nerve root decompression at lumbar disc herniation surgery by intraoperative ultrasound.</a> Ultrasound in Medicine &amp; Biology. 35 (6), 920-927 (2009).</li><li>Bose, B. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Thoracic+extruded+disc+mimicking+spinal+cord+tumor.">Thoracic extruded disc mimicking spinal cord tumor.</a> The Spine Journal: Official Journal of the North American Spine Society. 3 (1), 82-86 (2003).</li><li>Harel, R., Knoller, N. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Intraoperative+spine+ultrasound:+application+and+benefits.">Intraoperative spine ultrasound: application and benefits.</a> European Spine Journal: Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 25 (3), 865-869 (2016).</li><li>Lazennec, J. Y., Saillant, G., Hansen, S., Ramare, S. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Intraoperative+ultrasonography+evaluation+of+posterior+vertebral+wall+displacement+in+thoracolumbar+fractures.">Intraoperative ultrasonography evaluation of posterior vertebral wall displacement in thoracolumbar fractures.</a> Neurologia Medico-Chirurgica. 39 (1), 8-15 (1999).</li><li>Matsuyama, Y., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Cervical+myelopathy+due+to+OPLL:+clinical+evaluation+by+MRI+and+intraoperative+spinal+sonography.">Cervical myelopathy due to OPLL: clinical evaluation by MRI and intraoperative spinal sonography.</a> Journal of Spinal Disorders &amp; Techniques. 17 (5), 401-404 (2004).</li><li>Mueller, L. A., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Ultrasound-guided+spinal+fracture+repositioning,+ligamentotaxis,+and+remodeling+after+thoracolumbar+burst+fractures.">Ultrasound-guided spinal fracture repositioning, ligamentotaxis, and remodeling after thoracolumbar burst fractures.</a> Spine. 31 (20), 739-747 (2006).</li><li>Nishimura, Y., Thani, N. B., Tochigi, S., Ahn, H., Ginsberg, H. J. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Thoracic+discectomy+by+posterior+pedicle-sparing,+transfacet+approach+with+real-time+intraoperative+ultrasonography:+Clinical+article.">Thoracic discectomy by posterior pedicle-sparing, transfacet approach with real-time intraoperative ultrasonography: Clinical article.</a> Journal of Neurosurgery. Spine. 21 (4), 568-576 (2014).</li><li>Randel, S., Gooding, G. A., Dillon, W. P. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Sonography+of+intraoperative+spinal+arteriovenous+malformations.">Sonography of intraoperative spinal arteriovenous malformations.</a> Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine. 6 (9), 539-544 (1987).</li><li>Seichi, A., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Intraoperative+ultrasonographic+evaluation+of+posterior+decompression+via.+laminoplasty+in+patients+with+cervical+ossification+of+the+posterior+longitudinal+ligament:+correlation+with+2-year+follow-up+results.">Intraoperative ultrasonographic evaluation of posterior decompression via. laminoplasty in patients with cervical ossification of the posterior longitudinal ligament: correlation with 2-year follow-up results.</a> Journal of Neurosurgery. Spine. 13 (1), 47-51 (2010).</li><li>Tian, W., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Intraoperative+3-dimensional+navigation+and+ultrasonography+during+posterior+decompression+with+instrumented+fusion+for+ossification+of+the+posterior+longitudinal+ligament+in+the+thoracic+spine.">Intraoperative 3-dimensional navigation and ultrasonography during posterior decompression with instrumented fusion for ossification of the posterior longitudinal ligament in the thoracic spine.</a> Journal of Spinal Disorders &amp; Techniques. 26 (6), 227-234 (2013).</li><li>Tokuhashi, Y., Matsuzaki, H., Oda, H., Uei, H. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Effectiveness+of+posterior+decompression+for+patients+with+ossification+of+the+posterior+longitudinal+ligament+in+the+thoracic+spine:+usefulness+of+the+ossification-kyphosis+angle+on+MRI.">Effectiveness of posterior decompression for patients with ossification of the posterior longitudinal ligament in the thoracic spine: usefulness of the ossification-kyphosis angle on MRI.</a> Spine. 31 (1), 26-30 (2006).</li><li>Vasudeva, V. S., Abd-El-Barr, M., Pompeu, Y. A., Karhade, A., Groff, M. W., Lu, Y. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Use+of+Intraoperative+Ultrasound+During+Spinal+Surgery.">Use of Intraoperative Ultrasound During Spinal Surgery.</a> Global Spine Journal. 7 (7), 648-656 (2017).</li><li>Alaqeel, A., Abou Al-Shaar, H., Alaqeel, A., Al-Habib, A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=The+utility+of+ultrasound+for+surgical+spinal+decompression.">The utility of ultrasound for surgical spinal decompression.</a> Medical Ultrasonography. 17 (2), 211-218 (2015).</li><li>Della Pepa, G. 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Intraoperative ultrasound in the spinal surgery has largely fallen out of favor with the advent of newer technology, however, it continues to provide several advantages over the other available imaging modalities such as MRI and CT6,9,16,17,18. In addition to being inexpensive, in this protocol we also show that it is simple to use and can provide visualizatio...

Ultrasound is one of the most common diagnostic tools in medicine, particularly for visualizing pathology in the abdomen, limbs, and neck. However, its use to investigate cranial and spinal lesions is not currently widely utilized. In 1978, Reid was the first to report the use of ultrasound to visualize cervical cord cystic astrocytoma1. Here, scans were performed with the patient&#39;s neck flexed to allow opening of the intralaminar window. Four years later, in 1982, Dohrmann and Rubin reported the use of ultrasound intraoperatively to visualize the intradural space in 10 patients2. Pathologies identified with intraoperative ultrasound among the 10 patients included syringomyelia, spinal cord cysts, and intramedullary and extramedullary tumors. They further demonstrated the use of intraoperative ultrasound to guide catheters and probes for biopsy of tumors, drainage of cysts, and ventricular shunt catheter placement3. This allowed the real-time monitoring and precise positioning of probes/catheters, reducing inaccuracy and errors in placement. Following these initial reports, several others have published the use of intraoperative ultrasound for guiding spinal cord cyst drainage, intramedullary and extramedullary tumor resection, and syringo-subarachnoid shunt catheter placement4,5,6,7,8,9,10. Additionally, it has been shown to also increase rate of complete resection of intra-axial solid brain tumors and spinal intradural tumors11,12. Intraoperative ultrasound has also proven to be useful for the intraoperative surgical planning before manipulation of the tissue and subsequent visualization of adequate neural element decompression in patients with spine fractures7,9,13,14,15.
With the advent of newer intraoperative technology allowing clearer visualization of soft tissues, such as magnetic resonance imaging (MRI) and computed tomography (CT), intraoperative ultrasound has become less common and a less favored intraoperative imaging modality among neurosurgeons today16. However, intraoperative ultrasound can have advantages over these newer technologies in certain operative cases (Table 1). Intraoperative ultrasound has shown to demonstrate better soft tissue visualization of intradural structures when compared with intraoperative CT (iCT) or cone-beam CT (cbCT)9,17. While intraoperative MRI (iMRI) is useful where available because of the higher soft tissue resolution it provides, it is costly, time consuming and does not provide real-time images6, 16,18. An example is in the circumstance of an intradural mass ventral to the thecal sac that the surgeon is unable to directly visualize. Additionally, despite being operator dependent, from our experience, intraoperative ultrasound is fairly simple to use and can be easily read without a radiologist.

<table border="0" cellpadding="0" cellspacing="0" style="width:848px;" width="847">
	<tbody>
		<tr height="40">
			<td height="40" style="height:40px;width:215px;">Aloka Prosound 5 mobile ultrasound machine</td>
			<td style="width:123px;">Hitachi</td>
			<td style="width:344px;">N/A</td>
			<td style="width:167px;">any comparable devices on the market should suffice</td>
		</tr>
		<tr height="40">
			<td height="40" style="height:40px;">UST-9120 transducer probe.</td>
			<td>Hitachi</td>
			<td>UST-9120</td>
			<td>Has a 20mm diameter with 10 to 4.4 MHz frequency range (any comparable compatible transducer should suffice).</td>
		</tr>
	</tbody>
</table>

intraoperative ultrasound in spinal surgery

Since the 1980s, there have been several reports for the use of intraoperative ultrasound as a useful adjunct in spinal surgery. However, with the advent of newer cutting-edge imaging modalities, the use of intraoperative ultrasound in spine surgery has largely fallen out of favor. Despite this, intraoperative ultrasound continues to provide several advantages over other intraoperative techniques such as magnetic resonance imaging and computed tomography including being more cost-effective, efficient, and easy to operate and interpret. Additionally, it remains the only method for the real-time visualization of soft tissue and pathologies. This paper focuses on the advantages of using intraoperative ultrasound, especially in cases of intradural lesions and lesions ventral to the thecal sac when approaching posteriorly.

On normal spine ultrasound imaging, the dura is an echogenic layer that surrounds the anechoic spinal fluid. The spinal cord is distinguished by its homogenous appearance and low echogenicity which is surrounded by an echogenic rim. This echogenic rim is due to the density shift from the spinal fluid to the spinal cord. The central canal appears as a bright central echo, while exiting nerve roots appear highly echogenic, particularly at the cauda equina16. Intraope...

Watch this Scientific Journal Video about Intraoperative Ultrasound in Spinal Surgery at JoVE.com

Intraoperative Ultrasound in Spinal Surgery

Here, we present a protocol on the use of intraoperative ultrasound in spinal surgery, particularly in cases of intradural lesions and lesions in the ventral spinal canal when using a posterior approach.

Since the 1980s, there have been several reports for the use of intraoperative ultrasound as a useful adjunct in spinal surgery. However, with the advent ...

Intraoperative ultrasound for spine surgery is very useful for intradural pathology or ventral spinal cord pathology that allow the surgeon to visualize the lesion before opening dura. This also help the surgeon to locate where the lesion is and also to confirm the adequate decompression of the spinal cord after the lesion removal, tumor removal. It provides the real time information that's very, very useful for the spine surgeon during the case.The main advantage of this technique is to allow the surgeon to visualize the lesion intradurally before opening dura in the real time. Before beginning the procedure, perform a Magnetic Resonance Imaging, or MRI scan, to identify the spinal lesion. After general anesthesia administration, position the patient so the back is exposed, and sterilize the surgical area with a povidone-iodine scrub.Next, use a scalpel to make an incision along the length of the spine over the appropriate vertebrae levels. Continuing the incision down through the tissue until the bone is reached. Perform a subperiosteal dissection by electrosurgical cautery and expose the spinous process.Turn the cutting edge of the cautery ventrally, and sweep it across the laminar, and use a combination of a Lexer bone plier and a high speed drill to remove the bony lamina and spinous process to expose the ligamentum flavum underneath. Use an angled curette and Karrison bone punch to remove the ligamentum flavum to reveal the dura mater underneath. Then use a bipolar and hemostatic matrix to achieve hemostasis.After the bony removal and dura exposure, fill the surgical field with 100 to 500 Ml saline solution such that an ultrasound tranducer probe with a 20 mm diameter can be submerged. Turn on the mobile ultrasound machine and place the ultrasound probe within the saline bath at the level of interest to begin acquiring images. To visualize the spinal cord and the lesion similar to the sagittal images from the MRI move the probe in line with the direction of the spinal canal and acquire realtime images in the longitudinal plane.To visualize the spinal cord and the lesion, like the axial images from the MRI, place the probe perpendicular to the spinal canal and acquire real-time images in the transverse plane. Then acquire real-time images to verify the location of any lesions that cannot be directly visualized to correlate with the preoperative computer tomography or MRI images to guide the surgical tool placement, and/or to confirm the resolution of the pathology. Preoperative imaging approximates the location of an intradural mass with respect to its known adjacent structures.Here, the intraoperative ultrasound correlated with the preoperative MRI imaging revealing a fluid collection above the lesion site. An axial intraoperative ultrasound showed the mass encompassing the majority of the spinal cord and a 0.5 by 0.5 centimeter piece of sterile compressed sponge was used to confirm the card limit of the tumor. A post resection intraoperative ultrasound was then obtained to confirm a complete removal of the tumor and the resolution of the mass effect.In asymptomatic thoracic disc herniation, resection by a posterior approach an intraoperative ultrasound aided in evaluating the decompression and ensuring that all of the compressive disc fragments were excised. Similarly, in the case of a lumbar burst fracture, an intraoperative ultrasound was useful in confirming an adequate decompression and the removal of all of the fragments. So while performing the intra ultrasound for spine surgeries, is important to be patient and provide a wider view for the area and use a big probe to obtain a clean imaging.Take the patient to obtain nice clean axial and sagittal view of the spinal cord so that the relationship between the spinal cord and the tumor or the lesion is cleanly defined with the ultrasound images.

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4.4K ビュー.  Harvard Medical School. 脊椎手術のための術中超音波は、外科医が硬膜を開く前に病変を視覚化することを可能にする硬膜内病理または腹側脊髄病理に非常に有用である。これはまた、外科医が病変がどこにあるかを特定し、病変除去、腫瘍除去後の脊髄の適切な減圧を確認するのにも役立つ。これは、症例中に脊椎外科医にとって非常に、非常に有用なリアルタイム情報を提供します。?...

ビデオ: Intraoperative Ultrasound in Spinal Surgery

Here, we present a protocol on the use of intraoperative ultrasound in spinal surgery, particularly in cases of intradural lesions and lesions in the ventral spinal canal when using a posterior...

intraoperative gastroscopy for tumor localization in laparoscopic surgery for gastric adenocarcinoma

Intraoperative Gastroscopy for Tumor Localization in Laparoscopic Surgery for Gastric Adenocarcinoma

In early gastric cancer, the aim of surgery is to precisely remove the distal stomach including the primary tumor. To do this, accurate localization of the tumor is crucial, especially in totally laparoscopic surgery. This protocol describes a procedure for intraoperative gastroscopy in totally laparoscopic subtotal...

the third channel-assisted unilateral biportal endoscopic technique for lumbar spinal stenosis combined with contralateral disc herniation

Author Spotlight: Unveiling the Potential of TUBE Technique in Spinal Surgery

Here, we present the third channel-assisted UBE technique, which allows for the vertical removal of herniated disc fragments. This technique can effectively address the limitations of traditional UBE techniques. This article will systematically elaborate on this...

A 3-Channel Endoscopic Technique for Lumbar Stenosis and Contralateral Herniation

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contrast enhanced ultrasound imaging for assessment of spinal cord blood flow in experimental spinal cord injury

Contrast Enhanced Ultrasound Imaging for Assessment of Spinal Cord Blood Flow in Experimental Spinal Cord Injury

Contrast Enhanced Ultrasound imaging is a reliable in-vivo tool for quantifying spinal cord blood flow in an experimental rat spinal cord injury model. This paper contains a comprehensive protocol for application of this technique in association with a contusion model of thoracic spinal cord...

spinal shortening surgery for lumbosacral nerve bowstring disease: a surgical technique

Spinal Shortening Surgery for Lumbosacral Nerve Bowstring Disease: A Surgical Technique

Lumbosacral nerve bowstring disease (LNBD) is a syndrome comprising a series of neurological symptoms caused by high axial tension of the lumbosacral nerve due to congenital, iatrogenic, and other factors. Here, we introduce a surgical technique for the treatment of LNBD through spinal shortening...

thoracic spinal cord hemisection surgery and open-field locomotor assessment in the rat

Thoracic Spinal Cord Hemisection Surgery and Open-Field Locomotor Assessment in the Rat

The rat thoracic spinal hemisection is a valuable and reproducible model of unilateral spinal cord injury to investigate the neural mechanisms of locomotor recovery and treatment efficacy. This article includes a detailed step-by-step guide to perform the hemisection procedure and to assess locomotor performance in an open-field...

evaluation of the feasibility, safety, and accuracy of an intraoperative high-intensity focused ultrasound device for treating liver metastases

Evaluation of the Feasibility, Safety, and Accuracy of an Intraoperative High-intensity Focused Ultrasound Device for Treating Liver Metastases

Here, we present an ablate-and-resect prospective study to evaluate the feasibility, safety, and accuracy of intraoperative high-intensity focused ultrasound ablation in patients undergoing hepatectomy for liver...

biportal endoscopic surgery for lumbar spinal stenosis with contralateral disc herniation

Biportal Endoscopic Surgery for Lumbar Spinal Stenosis with Contralateral Disc Herniation

treating low back pain in failed back surgery patients with multicolumn-lead spinal cord stimulation

Treating Low Back Pain in Failed Back Surgery Patients with Multicolumn-lead Spinal Cord Stimulation

This paper presents a method that uses spinal cord stimulation with a multicolumn lead to treat neuropathic low back pain in failed back surgery...

a retrospective study on endoscopic surgery for the treatment of paravertebral abscess in spinal tuberculosis patients

This study evaluated endoscopic debridement for treating paravertebral abscesses in patients with spinal tuberculosis. Compared to conventional surgery, it significantly improved surgery time, blood loss, hospital stay, pain relief, and neurological outcomes, with fewer complications and no recurrences. These findings highlight its efficacy and safety. Further long-term studies are...

A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients

disruption of the blood-spinal cord barrier using low-intensity focused ultrasound in a rat model

Disruption of the Blood-Spinal Cord Barrier Using Low-Intensity Focused Ultrasound in a Rat Model

Disruption of the blood-spinal cord barrier (BSCB) can be successfully achieved with the intravenous administration of microbubbles and the application of low-intensity focused ultrasound (LIFU). This protocol details the opening of the BSCB using LIFU in a rodent model, including equipment setup, microbubble injection, target localization, and BSCB disruption visualization.

patient-specific polyvinyl alcohol phantom fabrication with ultrasound and x-ray contrast for brain tumor surgery planning

Patient-Specific Polyvinyl Alcohol Phantom Fabrication with Ultrasound and X-Ray Contrast for Brain Tumor Surgery Planning

This protocol describes the fabrication of a patient specific skull, brain and tumor phantom. It uses 3D printing to create molds, and polyvinyl alcohol (PVA-c) is used as the tissue mimicking...

application of laparoscopic hepatectomy combined with intraoperative microwave ablation in colorectal cancer liver metastasis

Application of Laparoscopic Hepatectomy Combined with Intraoperative Microwave Ablation in Colorectal Cancer Liver Metastasis

This protocol describes the laparoscopic resection of colorectal cancer liver metastases combined with ultrasound-guided microwave ablation. This technique can safely, effectively, and accurately treat refractory liver metastases &lt;3 cm, reduce postoperative complications, and accelerate the postoperative rehabilitation of...

electrically evoked stapedius reflex measurements in cochlear implantation and its application in the postoperative fitting process

Author Spotlight: Optimizing Cochlear Implant Performance in Children

The present protocol describes the measurement of the electrically evoked stapedius reflex (eSR) via cochlear implant (CI). Two applications are discussed: intraoperative detection of eSR for verification of the coupling between the cochlear implant and the auditory nerve and postoperative measurement of eSR thresholds (eSRT) for CI...

Measuring Electrically Evoked Stapedius Reflex for Cochlear Implant Fitting

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intraoperative assessment of resection margins in oral cavity cancer: this is the way

Intraoperative Assessment of Resection Margins in Oral Cavity Cancer: This is the Way

The goal of this protocol is to provide a clear overview of specimen-driven intraoperative assessment of resection margins. It is encouraged to implement this protocol to improve patient care at other...

cone beam intraoperative computed tomography-based image guidance for minimally invasive transforaminal interbody fusion

Cone Beam Intraoperative Computed Tomography-based Image Guidance for Minimally Invasive Transforaminal Interbody Fusion

The purpose of this article is to provide image-guidance for minimally invasive transforaminal interbody...

performing repeated intraoperative impedance telemetry measurements during cochlear implantation

Author Spotlight: Advancements in Impedance Monitoring for Cochlear Implant Surgery

Here we present a protocol to conduct repeated impedance telemetry measurements during cochlear implantation (CI). They may allow conclusions on the electrode's and implant's function. Repeated impedance measurements enable objective feedback on whether the electrode is positioned inside the perilymph or outside the inner...

Performing Repeated Intraoperative Impedance Telemetry Measurements during Cochlear Implantation

multispectral real-time fluorescence imaging for intraoperative detection of the sentinel lymph node in gynecologic oncology

Multispectral Real-time Fluorescence Imaging for Intraoperative Detection of the Sentinel Lymph Node in Gynecologic Oncology

Fluorescence imaging is a promising innovative modality for image-guided surgery in surgical oncology. In this video we describe the technical procedure for detection of the sentinel lymph node using fluorescence imaging as showcased in gynecologic oncologicy. A multispectral fluorescence camera system, together with the fluorescent agent indocyanine green, is...

biomechanical analysis of adjacent segments after spinal fusion surgery using a geometrically parametric patient-specific finite element model

Biomechanical Analysis of Adjacent Segments after Spinal Fusion Surgery Using a Geometrically Parametric Patient-Specific Finite Element Model

Here, we used a patient-specific finite element model to analyze the mechanical changes in adjacent segments after spinal fusion surgery. The results showed that fusion surgery reduced the overall motion of the lumbar spine but increased the load on and stress in adjacent segments, especially the proximal...

The prognosis in virtually all solid tumors depends on the presence or absence of lymph node metastases.1-3 Surgical treatment most often combines radical excision of the tumor with a full lymphadenectomy in the drainage area of the tumor. However, removal of lymph nodes is associated with increased morbidity due to infection, wound breakdown and lymphedema.4,5 As an alternative, the sentinel lymph node procedure (SLN) was developed several decades ago to detect the first draining lymph node from the tumor.6 In case of lymphogenic dissemination, the SLN is the first lymph node that is affected (Figure 1). Hence, if the SLN does not contain metastases, downstream lymph nodes will also be free from tumor metastases and need not to be removed. The SLN procedure is part of the treatment for many tumor types, like breast cancer and melanoma, but also for cancer of the vulva and cervix.7 The current standard methodology for SLN-detection is by peritumoral injection of radiocolloid one day prior to surgery, and a colored dye intraoperatively. Disadvantages of the procedure in cervical and vulvar cancer are multiple injections in the genital area, leading to increased psychological distress for the patient, and the use of radioactive colloid.
Multispectral fluorescence imaging is an emerging imaging modality that can be applied intraoperatively without the need for injection of radiocolloid. For intraoperative fluorescence imaging, two components are needed: a fluorescent agent and a quantitative optical system for intraoperative imaging. As a fluorophore we have used indocyanine green (ICG). ICG has been used for many decades to assess cardiac function, cerebral perfusion and liver perfusion.8 It is an inert drug with a safe pharmaco-biological profile. When excited at around 750 nm, it emits light in the near-infrared spectrum around 800 nm. A custom-made multispectral fluorescence imaging camera system was used.9.
The aim of this video article is to demonstrate the detection of the SLN using intraoperative fluorescence imaging in patients with cervical and vulvar cancer. Fluorescence imaging is used in conjunction with the standard procedure, consisting of radiocolloid and a blue dye. In the future, intraoperative fluorescence imaging might replace the current method and is also easily transferable to other indications like breast cancer and melanoma.

Fluorescence imaging is a promising innovative modality for image-guided surgery in surgical oncology. In this video we describe the technical procedure for detection of the sentinel lymph node using fluorescence imaging as showcased in gynecologic oncologicy. A multispectral fluorescence camera system, together with the fluorescent agent indocyanine green, is applied.

The prognosis in virtually all solid tumors depends on the presence or absence of lymph node metastases.1-3 Surgical treatment most often combines radical ...

Acute and Chronic Tactile Sensory Testing after Spinal Cord Injury in Rats

Spinal cord injury (SCI) impairs sensory systems causing allodynia1-8. To identify cellular and molecular causes of allodynia, sensitive and valid sensory testing in rat SCI models is needed. However, until recently, no single testing approach had been validated for SCI so that standardized methods have not been implemented across labs. Additionally, available testing methods could not be implemented acutely or when severe motor impairments existed, preventing studies of the development of SCI-induced allodynia3. Here we present two validated sensory testing methods using von Frey Hair (VFH) monofilaments which quantify changes in tactile sensory thresholds after SCI4-5. One test is the well-established Up-Down test which demonstrates high sensitivity and specificity across different SCI severities when tested chronically5. The other test is a newly-developed dorsal VFH test that can be applied acutely after SCI when allodynia develops, prior to motor recovery4-5. Each VFH monofilament applies a calibrated force when touched to the skin of the hind paw until it bends. In the up-down method, alternating VFHs of higher or lower forces are used on the plantar L5 dermatome to delineate flexor withdrawal thresholds. Successively higher forces are applied until withdrawal occurs then lower force VFHs are used until withdrawal ceases. The tactile threshold reflects the force required to elicit withdrawal in 50% of the stimuli. For the new test, each VFH is applied to the dorsal L5 dermatome of the paw while the rat is supported by the examiner. The VFH stimulation occurs in ascending order of force until at least 2 of 3 applications at a given force produces paw withdrawal. Tactile sensory threshold is the lowest force to elicit withdrawal 66% of the time. Acclimation, testing and scoring procedures are described. Aberrant trials that require a retest and typical trials are defined. Animal use was approved by Ohio State University Animal Care and Use Committee.

We describe two tactile sensory testing methods for acute or chronic periods of spinal cord injury in rats. These validated procedures can detect the development and maintenance of allodynia-like sensations.

Spinal cord injury (SCI) impairs sensory systems causing allodynia1-8. To identify cellular and molecular causes of allodynia, sensitive and valid sensory ...

Controlled Cortical Impact Model for Traumatic Brain Injury

Every year over a million Americans suffer a traumatic brain injury (TBI). Combined with the incidence of TBIs worldwide, the physical, emotional, social, and economical effects are staggering. Therefore, further research into the effects of TBI and effective treatments is necessary. The controlled cortical impact (CCI) model induces traumatic brain injuries ranging from mild to severe. This method uses a rigid impactor to deliver mechanical energy to an intact dura exposed following a craniectomy. Impact is made under precise parameters at a set velocity to achieve a pre-determined deformation depth. Although other TBI models, such as weight drop and fluid percussion, exist, CCI is more accurate, easier to control, and most importantly, produces traumatic brain injuries similar to those seen in humans. However, no TBI model is currently able to reproduce pathological changes identical to those seen in human patients. The CCI model allows investigation into the short-term and long-term effects of TBI, such as neuronal death, memory deficits, and cerebral edema, as well as potential therapeutic treatments for TBI.

Traumatic brain injuries (TBIs) remain a serious health problem. Using the controlled cortical impact surgery model, research on the effects of TBI and possible treatment methods may be performed.

Every year over a million Americans suffer a traumatic brain injury (TBI).  Combined with the incidence of TBIs worldwide, the physical, emotional, ...

Reduced spinal cord blood flow (SCBF) (i.e., ischemia) plays a key role in traumatic spinal cord injury (SCI) pathophysiology and is accordingly an important target for neuroprotective therapies. Although several techniques have been described to assess SCBF, they all have significant limitations. To overcome the latter, we propose the use of real-time contrast enhanced ultrasound imaging (CEU). Here we describe the application of this technique in a rat contusion model of SCI. A jugular catheter is first implanted for the repeated injection of contrast agent, a sodium chloride solution of sulphur hexafluoride encapsulated microbubbles. The spine is then stabilized with a custom-made 3D-frame and the spinal cord dura mater is exposed by a laminectomy at ThIX-ThXII. The ultrasound probe is then positioned at the posterior aspect of the dura mater (coated with ultrasound gel). To assess baseline SCBF, a single intravenous injection (400 &#181;l) of contrast agent is applied to record its passage through the intact spinal cord microvasculature. A weight-drop device is subsequently used to generate a reproducible experimental contusion model of SCI. Contrast agent is re-injected 15 min following the injury to assess post-SCI SCBF changes. CEU allows for real time and in-vivo assessment of SCBF changes following SCI. In the uninjured animal, ultrasound imaging showed uneven blood flow along the intact spinal cord. Furthermore, 15 min post-SCI, there was critical ischemia at the level of the epicenter while SCBF remained preserved in the more remote intact areas. In the regions adjacent to the epicenter (both rostral and caudal), SCBF was significantly reduced. This corresponds to the previously described &#8220;ischemic penumbra zone&#8221;. This tool is of major interest for assessing the effects of therapies aimed at limiting ischemia and the resulting tissue necrosis subsequent to SCI.

Contrast Enhanced Ultrasound imaging is a reliable in-vivo tool for quantifying spinal cord blood flow in an experimental rat spinal cord injury model. This paper contains a comprehensive protocol for application of this technique in association with a contusion model of thoracic spinal cord injury.

Reduced spinal cord blood flow (SCBF) (i.e., ischemia) plays a key role in traumatic spinal cord injury (SCI) pathophysiology and is accordingly an ...

Determining resection margins for gastric cancer, which are not exposed to the serosal surface of the stomach, is the most important procedure during totally laparoscopic gastrectomy (TLG). The aim of this protocol is to introduce a procedure for intraoperative gastroscopy, in order to directly mark tumors during TLG for gastric cancer in the middle third of the stomach. Patients who were diagnosed with adenocarcinoma in the middle third of the stomach were enrolled in this case series. Before surgery, additional gastroscopy for tumor localization is not performed. Under general anesthesia, laparoscopic mobilization of the stomach is performed first. After the first portion of the duodenum is mobilized from the pancreas and clamped, the surgeon moves to the other side for the gastroscopic procedure. On the insertion of a gastroscope through the oral cavity into the stomach, 2 - 3 cc of indigo carmine is administered via an endoscopic injector into the gastric muscle layer at the proximal margin of the stomach. The location of stained serosa in the laparoscopic view is used to guide distal subtotal gastrectomy, however, total gastrectomy is performed if the tumor is too close to the esophagogastric junction. A specimen is sampled after distal gastrectomy to confirm sufficient length from resection margin to tumor before reconstruction. In our case series, all patients had tumor-free margins and required no additional resection. There was no morbidity related to the gastroscopic procedure, and the time required for the procedure has gradually decreased to about five minutes. Intraoperative gastroscopy for tumor localization is an accurate and tolerated method for gastric cancer patients undergoing totally laparoscopic distal gastrectomy.

In early gastric cancer, the aim of surgery is to precisely remove the distal stomach including the primary tumor. To do this, accurate localization of the tumor is crucial, especially in totally laparoscopic surgery. This protocol describes a procedure for intraoperative gastroscopy in totally laparoscopic subtotal gastrectomy.

Determining resection margins for gastric cancer, which are not exposed to the serosal surface of the stomach, is the most important procedure during ...

Transforaminal lumbar interbody fusion (TLIF) is commonly used for the treatment of spinal stenosis, degenerative disc disease, and spondylolisthesis. Minimally invasive surgery (MIS) approaches have been applied to this technique with an associated decrease in estimated blood loss (EBL), length of hospital stay, and infection rates, while preserving outcomes with traditional open surgery. Previous MIS TLIF techniques involve significant fluoroscopy that subjects the patient, surgeon, and operating room staff to non-trivial levels of radiation exposure, particularly for complex multi-level procedures. We present a technique that utilizes an intraoperative computed tomography (CT) scan to aid in placement of pedicle screws, followed by traditional fluoroscopy for confirmation of cage placement. Patients are positioned in the standard fashion and a reference arc is placed in the posterior superior iliac spine (PSIS) followed by intraoperative CT scan. This allows for image-guidance-based placement of pedicle screws through a one-inch skin incision on each side. Unlike traditional MIS-TLIF that requires significant fluoroscopic imaging during this stage, the operation can now be performed without any additional radiation exposure to the patient or operating room staff. After completion of the facetectomy and discectomy, final TLIF cage placement is confirmed with fluoroscopy. This technique has the potential to decrease operative time and minimize total radiation exposure.

The purpose of this article is to provide image-guidance for minimally invasive transforaminal interbody fusion.

Transforaminal lumbar interbody fusion (TLIF) is commonly used for the treatment of spinal stenosis, degenerative disc disease, and spondylolisthesis. ...

The goal of head and neck oncological surgery is complete tumor resection with adequate resection margins while preserving acceptable function and appearance. For oral cavity squamous cell carcinoma (OCSCC), different studies showed that only 15%-26% of all resections are adequate. A major reason for the low number of adequate resections is the lack of information during surgery; the margin status is only available after the final histopathologic assessment, days after surgery.
The surgeons and pathologists at the Erasmus MC University Medical Center in Rotterdam started the implementation of specimen-driven intraoperative assessment of resection margins (IOARM) in 2013, which became the standard of care in 2015. This method enables the surgeon to turn an inadequate resection into an adequate resection by performing an additional resection during the initial surgery. Intraoperative assessment is supported by a relocation method procedure that allows accurate identification of inadequate margins (found on the specimen) in the wound bed.
The implementation of this protocol resulted in an improvement of adequate resections from 15%-40%. However, the specimen-driven IOARM is not widely adopted because grossing fresh tissue is counter-intuitive for pathologists. The fear exists that grossing fresh tissue will deteriorate the anatomical orientation, shape, and size of the specimen and therefore will affect the final histopathologic assessment. These possible negative effects are countered by the described protocol. Here, the protocol for specimen-driven IOARM is presented in detail, as performed at the institute.

The goal of this protocol is to provide a clear overview of specimen-driven intraoperative assessment of resection margins. It is encouraged to implement this protocol to improve patient care at other institutes.

The goal of head and neck oncological surgery is complete tumor resection with adequate resection margins while preserving acceptable function and ...

Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction

Patients with unresectable malignant biliary obstruction often require biliary drainage to decompress the biliary system. Endoscopic Retrograde Cholangiopancreatography (ERCP) is the primary biliary drainage method whenever possible. Percutaneous Transhepatic Biliary Drainage (PTBD) is used as a salvage method if ERCP fails. Endoscopic Ultrasound-Guided Biliary Drainage (EUS-BD) provides a feasible alternative biliary drainage method where one of the methods is EUS guided Hepaticogastrostomy (EUS-HGS). Here we describe the EUS-HGS technique in a case of unresectable malignant hilar biliary obstruction to achieve biliary drainage.
Presented here is the case of a 71-year-old female with painless jaundice and weight loss for 2 weeks. Computed Tomography (CT) imaging showed a 4 x 5 cm hilar tumor with lymphadenopathy and liver metastasis. EUS fine needle biopsy (FNB) of the lesion was consistent with cholangiocarcinoma. Her bilirubin levels were 212 &#181;mol/L (&lt;15) during presentation.
A linear echoendoscope was used to locate the left dilated intrahepatic ducts (IHD) of the liver. The segment 3 dilated IHD was identified and punctured using a 19 G needle. Contrast was used to opacify the IHDs under fluoroscopic guidance. The IHD was cannulated using a 0.025-inch guidewire. This was followed by the dilation of the fistula tract using a 6 Fr electrocautery dilator along with a 4 mm biliary balloon dilator. A partially covered metallic stent of 10 cm in length was deployed under fluoroscopic guidance. The distal part opens in the IHD and the proximal part was deployed within the working channel of the echoendoscope that subsequently released into the stomach. The patient was discharged three days after the procedure. Follow up performed in the second and fourth weeks showed that the bilirubin levels were 30 &#181;mol/L and 14 &#181;mol/L, respectively. This indicates that EUS-HGS is a safe method for biliary drainage in unresectable malignant biliary obstruction.

Endoscopic Ultrasound-Guided Biliary Drainage (EUS-BD) is an alternative method of biliary decompression in malignant biliary obstruction. Here we describe the technique of EUS guided-Hepaticogastrostomy (EUS-HGS) in a case of unresectable malignant hilar biliary obstruction.

Patients with unresectable malignant biliary obstruction often require biliary drainage to decompress the biliary system. Endoscopic Retrograde ...

Orthopedic Robot-Assisted Femoral Neck System in the Treatment of Femoral Neck Fracture

Cannulated screw fixation is the main therapy for femoral neck fractures, especially in young patients. The traditional surgical procedure uses C-arm fluoroscopy to place the screw freehand and requires several guide wire adjustments, which increases the operation time and radiation exposure. Repeated drilling can also cause damage to the blood supply and bone quality of the femoral neck, which can be followed by complications such as screw loosening, nonunion, and femoral head necrosis. In order to make fixation more precise and reduce the incidence of complications, our team applied robot-assisted orthopedic surgery for screw placement using the femoral neck system to modify the traditional procedure. This protocol introduces how to import a patient's X-ray information into the system, how to perform screw path planning in software, and how the robotic arm assists in screw placement. Using this method, the surgeons can place the screw successfully the first time, improve the accuracy of the procedure, and avoid radiation exposure. The whole protocol includes the diagnosis of femoral neck fracture; the collection of intraoperative X-ray images; screw path planning in the software; precise placement of the screw under the assistance of the robotic arm by the surgeon; and verification of the implant placement.

This article introduces a method of robot-assisted orthopedic surgery for screw placement during the treatment of femoral neck fracture using the femoral neck system, which allows for more accurate screw placement, improved surgical efficiency, and fewer complications.

Cannulated screw fixation is the main therapy for femoral neck fractures, especially in young patients. The traditional surgical procedure uses C-arm ...

Laparoscopic hepatectomy is a common treatment for colorectal cancer liver metastasis. Previously, a sufficient number of functional liver masses had to be maintained during laparoscopic hepatectomy, with a residual liver volume of &gt;40% in cirrhotic patients and &gt;30% in non-cirrhotic patients. The high incidence of complications such as bleeding, bile leakage, or liver failure due to the exposure and difficulty of the resection of specific liver segments such as S2 and S7 reduces the success rate of liver resection. At present, microwave ablation is mainly applied in the treatment of liver metastasis using a percutaneous approach, which makes it difficult to identify hidden parts or small lesions. For some liver segments, the percutaneous puncture of liver segment 7 (S7) is likely to pass through the thoracic cavity, and the percutaneous puncture of liver segment 2 (S2) adjacent to the diaphragm is likely to injure the diaphragm and heart; these issues restrict the application of percutaneous ablation in colorectal cancer liver metastasis. Considering multiple lesions, laparoscopic microwave ablation combined with hepatectomy was performed in this study. The location of the lesions was determined by contrast-enhanced ultrasound under laparoscopy, and small lesions that were difficult to detect before the operation were identified. For the scattered lesions, which had diameters less than 3 cm and were difficult to resect, ablation was adopted to substitute hepatectomy. This technique helped to more explicitly locate the tumors, simplified the operation procedures, reduced the risk of complications such as bleeding and bile leakage, shortened the operation time, accelerated the postoperative recovery, significantly improved the success rate of operation, and enhanced the clinical prognosis of colorectal cancer liver metastasis by surgical resection.

This protocol describes the laparoscopic resection of colorectal cancer liver metastases combined with ultrasound-guided microwave ablation. This technique can safely, effectively, and accurately treat refractory liver metastases &lt;3 cm, reduce postoperative complications, and accelerate the postoperative rehabilitation of patients.

Laparoscopic hepatectomy is a common treatment for colorectal cancer liver metastasis. Previously, a sufficient number of functional liver masses had to ...